Abstract :

or the last two decades, Bioceramics Group of CSIR-Central Glass and Ceramic Research Institute (CSIRCGCRI), Kolkata has been engaged in the development of new generation of ceramic materials for different biomedical applications. The group has developed hip joint prosthesis with ceramic heads, hydroxyapatitebased bone fillers and ocular implants which after successful animal trials have been assessed through clinical trials at diferent hospitals (Calcutta Medical Research Institute, Kolkata; Advanced Medical Research Institute, Kolkata, All India Institute of Medical Sciences, New Delhi and Moulana Azad Medical College, New Delhi for hip implants and bone fillers and Eye Care and Research Centre, Kolkata; All India Institute of Medical Sciences, New Delhi, Sir Gangaram Hospital, New Delhi, Moulana Azad Medical College, New Delhi, Shankara Nethralaya, Chennai, Sri Sankardeva Nethralaya, Guwahati, Sarojini Devi Eye Hospital, Hyderabad and Disha Eye Hospital, Barackpore) in the country. These technologies have been commercialized and available in Indian market through M/s IFGL Bioceramics Ltd., Kolkata since January, 2005. Thereafter, few of the technologies have been transferred to other Indian companies who are in the process of obtaining manufacturing license from DCGI before commercialization. The Institute has also developed coatings on metallic implants by plasma spraying hydroxyapatite/other calcium phosphates for cementless fixation in the human subjects. These clinical trailswere primarily carried out at Sancheti Institute of Orthopedic and Rehabilitation, Pune under the leaderships of Padmavibhushan Dr. K.H. Sancheti. Further, the Institute has also actively participated in few CSIR network programmes to develop coated implants using diamond-like nano-composite (DLN) and standardize laser engineered net shaping (LENS) process for development of patient specific prosthesis of irregular shapes.

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